HCV Ag quantification as a one-step procedure in diagnosing chronic hepatitis C infection in Cameroon: the ANRS 12336 study.
Identifieur interne : 000784 ( Main/Exploration ); précédent : 000783; suivant : 000785HCV Ag quantification as a one-step procedure in diagnosing chronic hepatitis C infection in Cameroon: the ANRS 12336 study.
Auteurs : Léa Duchesne [France] ; Richard Njouom [Cameroun] ; Frédéric Lissock [Cameroun] ; Gishlaine Flore Tamko-Mella [Cameroun] ; Sandrine Rallier [France] ; Lila Poiteau [France] ; Alexandre Soulier [France] ; Stéphane Chevaliez [France] ; Guy Vernet [Cameroun] ; Nicolas Rouveau [France] ; Jean-Michel Pawlotsky [France] ; Pierre-Marie Girard [France] ; Karine Lacombe [France]Source :
- Journal of the International AIDS Society [ 1758-2652 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Anticorps de l'hépatite C (sang), Antigènes de l'hépatite C (sang), Cameroun (épidémiologie), Co-infection, Courbe ROC, Femelle, Humains, Hépatite B (), Hépatite C chronique (), Hépatite C chronique (diagnostic), Hépatite C chronique (virologie), Hépatite C chronique (épidémiologie), Infections à VIH (), Infections à VIH (épidémiologie), Mâle, Sensibilité et spécificité, Sujet âgé, Études transversales.
- MESH :
- diagnostic : Hépatite C chronique.
- sang : Anticorps de l'hépatite C, Antigènes de l'hépatite C.
- virologie : Hépatite C chronique.
- épidémiologie : Cameroun, Hépatite C chronique, Infections à VIH.
- Adulte, Adulte d'âge moyen, Co-infection, Courbe ROC, Femelle, Humains, Hépatite B, Hépatite C chronique, Infections à VIH, Mâle, Sensibilité et spécificité, Sujet âgé, Études transversales.
English descriptors
- KwdEn :
- Adult, Aged, Cameroon (epidemiology), Coinfection, Cross-Sectional Studies, Female, HIV Infections (complications), HIV Infections (epidemiology), Hepatitis B (complications), Hepatitis C Antibodies (blood), Hepatitis C Antigens (blood), Hepatitis C, Chronic (complications), Hepatitis C, Chronic (diagnosis), Hepatitis C, Chronic (epidemiology), Hepatitis C, Chronic (virology), Humans, Male, Middle Aged, ROC Curve, Sensitivity and Specificity.
- MESH :
- chemical , blood : Hepatitis C Antibodies, Hepatitis C Antigens.
- complications : HIV Infections, Hepatitis B, Hepatitis C, Chronic.
- diagnosis : Hepatitis C, Chronic.
- epidemiology : Cameroon, HIV Infections, Hepatitis C, Chronic.
- virology : Hepatitis C, Chronic.
- Adult, Aged, Coinfection, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, ROC Curve, Sensitivity and Specificity.
Abstract
The diagnostic procedure for chronic hepatitis C infection (CHC) usually combines anti-HCV antibody (HCV-Ab) and HCV-RNA measurement. Quantifying HCV core antigen (cAg) as a one-step procedure could shorten the diagnostic process. We aimed to assess the performance of cAg quantification in diagnosing CHC and how it is influenced by concomitant HIV or HBV infections.
DOI: 10.7448/IAS.20.1.21446
PubMed: 28530032
Affiliations:
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ANRS 12336 study.</title><author><name sortKey="Duchesne, Lea" sort="Duchesne, Lea" uniqKey="Duchesne L" first="Léa" last="Duchesne">Léa Duchesne</name><affiliation wicri:level="3"><nlm:affiliation>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Njouom, Richard" sort="Njouom, Richard" uniqKey="Njouom R" first="Richard" last="Njouom">Richard Njouom</name><affiliation wicri:level="1"><nlm:affiliation>Virology Department, Pasteur Center of Cameroun, Yaoundé, Cameroon.</nlm:affiliation><country xml:lang="fr">Cameroun</country><wicri:regionArea>Virology Department, Pasteur Center of Cameroun, Yaoundé</wicri:regionArea><wicri:noRegion>Yaoundé</wicri:noRegion></affiliation></author><author><name sortKey="Lissock, Frederic" sort="Lissock, Frederic" uniqKey="Lissock F" first="Frédéric" last="Lissock">Frédéric Lissock</name><affiliation wicri:level="1"><nlm:affiliation>Virology Department, Pasteur Center of Cameroun, Yaoundé, Cameroon.</nlm:affiliation><country xml:lang="fr">Cameroun</country><wicri:regionArea>Virology Department, Pasteur Center of Cameroun, Yaoundé</wicri:regionArea><wicri:noRegion>Yaoundé</wicri:noRegion></affiliation></author><author><name sortKey="Tamko Mella, Gishlaine Flore" sort="Tamko Mella, Gishlaine Flore" uniqKey="Tamko Mella G" first="Gishlaine Flore" last="Tamko-Mella">Gishlaine Flore Tamko-Mella</name><affiliation wicri:level="1"><nlm:affiliation>Virology Department, Pasteur Center of Cameroun, Yaoundé, Cameroon.</nlm:affiliation><country xml:lang="fr">Cameroun</country><wicri:regionArea>Virology Department, Pasteur Center of Cameroun, Yaoundé</wicri:regionArea><wicri:noRegion>Yaoundé</wicri:noRegion></affiliation></author><author><name sortKey="Rallier, Sandrine" sort="Rallier, Sandrine" uniqKey="Rallier S" first="Sandrine" last="Rallier">Sandrine Rallier</name><affiliation wicri:level="3"><nlm:affiliation>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Créteil</settlement></placeName></affiliation></author><author><name sortKey="Poiteau, Lila" sort="Poiteau, Lila" uniqKey="Poiteau L" first="Lila" last="Poiteau">Lila Poiteau</name><affiliation wicri:level="3"><nlm:affiliation>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Créteil</settlement></placeName></affiliation></author><author><name sortKey="Soulier, Alexandre" sort="Soulier, Alexandre" uniqKey="Soulier A" first="Alexandre" last="Soulier">Alexandre Soulier</name><affiliation wicri:level="3"><nlm:affiliation>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Créteil</settlement></placeName></affiliation></author><author><name sortKey="Chevaliez, Stephane" sort="Chevaliez, Stephane" uniqKey="Chevaliez S" first="Stéphane" last="Chevaliez">Stéphane Chevaliez</name><affiliation wicri:level="3"><nlm:affiliation>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Créteil</settlement></placeName></affiliation></author><author><name sortKey="Vernet, Guy" sort="Vernet, Guy" uniqKey="Vernet G" first="Guy" last="Vernet">Guy Vernet</name><affiliation wicri:level="1"><nlm:affiliation>Virology Department, Pasteur Center of Cameroun, Yaoundé, Cameroon.</nlm:affiliation><country xml:lang="fr">Cameroun</country><wicri:regionArea>Virology Department, Pasteur Center of Cameroun, Yaoundé</wicri:regionArea><wicri:noRegion>Yaoundé</wicri:noRegion></affiliation></author><author><name sortKey="Rouveau, Nicolas" sort="Rouveau, Nicolas" uniqKey="Rouveau N" first="Nicolas" last="Rouveau">Nicolas Rouveau</name><affiliation wicri:level="3"><nlm:affiliation>"Research in Resource-Limited Settings" Department, ANRS, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>"Research in Resource-Limited Settings" Department, ANRS, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Pawlotsky, Jean Michel" sort="Pawlotsky, Jean Michel" uniqKey="Pawlotsky J" first="Jean-Michel" last="Pawlotsky">Jean-Michel Pawlotsky</name><affiliation wicri:level="3"><nlm:affiliation>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>National Reference Center for Viral Hepatitis B, C and delta, Department of Virology, Hôpital Henri Mondor, Inserm U955, Université Paris-Est, Créteil</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Créteil</settlement></placeName></affiliation></author><author><name sortKey="Girard, Pierre Marie" sort="Girard, Pierre Marie" uniqKey="Girard P" first="Pierre-Marie" last="Girard">Pierre-Marie Girard</name><affiliation wicri:level="3"><nlm:affiliation>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lacombe, Karine" sort="Lacombe, Karine" uniqKey="Lacombe K" first="Karine" last="Lacombe">Karine Lacombe</name><affiliation wicri:level="3"><nlm:affiliation>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Institut Pierre Louis d'épidémiologie et de Santé Publique (IPLESP UMRS 1136), Sorbonne Universités, UPMC Univ Paris 06, Inserm, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author></analytic><series><title level="j">Journal of the International AIDS Society</title><idno type="eISSN">1758-2652</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Cameroon (epidemiology)</term><term>Coinfection</term><term>Cross-Sectional Studies</term><term>Female</term><term>HIV Infections (complications)</term><term>HIV Infections (epidemiology)</term><term>Hepatitis B (complications)</term><term>Hepatitis C Antibodies (blood)</term><term>Hepatitis C Antigens (blood)</term><term>Hepatitis C, Chronic (complications)</term><term>Hepatitis C, Chronic (diagnosis)</term><term>Hepatitis C, Chronic (epidemiology)</term><term>Hepatitis C, Chronic (virology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>ROC Curve</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Anticorps de l'hépatite C (sang)</term><term>Antigènes de l'hépatite C (sang)</term><term>Cameroun (épidémiologie)</term><term>Co-infection</term><term>Courbe ROC</term><term>Femelle</term><term>Humains</term><term>Hépatite B ()</term><term>Hépatite C chronique ()</term><term>Hépatite C chronique (diagnostic)</term><term>Hépatite C chronique (virologie)</term><term>Hépatite C chronique (épidémiologie)</term><term>Infections à VIH ()</term><term>Infections à VIH (épidémiologie)</term><term>Mâle</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Hepatitis C Antibodies</term><term>Hepatitis C Antigens</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term><term>Hepatitis B</term><term>Hepatitis C, Chronic</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Hepatitis C, Chronic</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Hépatite C chronique</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Cameroon</term><term>HIV Infections</term><term>Hepatitis C, Chronic</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps de l'hépatite C</term><term>Antigènes de l'hépatite C</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Hépatite C chronique</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Hepatitis C, Chronic</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Cameroun</term><term>Hépatite C chronique</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Coinfection</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>ROC Curve</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Co-infection</term><term>Courbe ROC</term><term>Femelle</term><term>Humains</term><term>Hépatite B</term><term>Hépatite C chronique</term><term>Infections à VIH</term><term>Mâle</term><term>Sensibilité et spécificité</term><term>Sujet âgé</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The diagnostic procedure for chronic hepatitis C infection (CHC) usually combines anti-HCV antibody (HCV-Ab) and HCV-RNA measurement. Quantifying HCV core antigen (cAg) as a one-step procedure could shorten the diagnostic process. We aimed to assess the performance of cAg quantification in diagnosing CHC and how it is influenced by concomitant HIV or HBV infections.</div></front></TEI><affiliations><list><country><li>Cameroun</li><li>France</li></country><region><li>Île-de-France</li></region><settlement><li>Créteil</li><li>Paris</li></settlement></list><tree><country name="France"><region name="Île-de-France"><name sortKey="Duchesne, Lea" sort="Duchesne, Lea" uniqKey="Duchesne L" first="Léa" last="Duchesne">Léa Duchesne</name></region><name sortKey="Chevaliez, Stephane" sort="Chevaliez, Stephane" uniqKey="Chevaliez S" first="Stéphane" last="Chevaliez">Stéphane Chevaliez</name><name sortKey="Girard, Pierre Marie" sort="Girard, Pierre Marie" uniqKey="Girard P" first="Pierre-Marie" last="Girard">Pierre-Marie Girard</name><name sortKey="Lacombe, Karine" sort="Lacombe, Karine" uniqKey="Lacombe K" first="Karine" last="Lacombe">Karine Lacombe</name><name sortKey="Pawlotsky, Jean Michel" sort="Pawlotsky, Jean Michel" uniqKey="Pawlotsky J" first="Jean-Michel" last="Pawlotsky">Jean-Michel Pawlotsky</name><name sortKey="Poiteau, Lila" sort="Poiteau, Lila" uniqKey="Poiteau L" first="Lila" last="Poiteau">Lila Poiteau</name><name sortKey="Rallier, Sandrine" sort="Rallier, Sandrine" uniqKey="Rallier S" first="Sandrine" last="Rallier">Sandrine Rallier</name><name sortKey="Rouveau, Nicolas" sort="Rouveau, Nicolas" uniqKey="Rouveau N" first="Nicolas" last="Rouveau">Nicolas Rouveau</name><name sortKey="Soulier, Alexandre" sort="Soulier, Alexandre" uniqKey="Soulier A" first="Alexandre" last="Soulier">Alexandre Soulier</name></country><country name="Cameroun"><noRegion><name sortKey="Njouom, Richard" sort="Njouom, Richard" uniqKey="Njouom R" first="Richard" last="Njouom">Richard Njouom</name></noRegion><name sortKey="Lissock, Frederic" sort="Lissock, Frederic" uniqKey="Lissock F" first="Frédéric" last="Lissock">Frédéric Lissock</name><name sortKey="Tamko Mella, Gishlaine Flore" sort="Tamko Mella, Gishlaine Flore" uniqKey="Tamko Mella G" first="Gishlaine Flore" last="Tamko-Mella">Gishlaine Flore Tamko-Mella</name><name sortKey="Vernet, Guy" sort="Vernet, Guy" uniqKey="Vernet G" first="Guy" last="Vernet">Guy Vernet</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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